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. Author manuscript; available in PMC: 2013 Apr 2.
Published in final edited form as: J Allergy Ther. 2011 Sep 20;2011(Suppl 1):001. doi: 10.4172/2155-6121.S1-001

Figure 1. Airway physiology measurements in C57BL/6 and Mindin −/− mice after saline or FAP.

Figure 1

C57BL/6 and Mindin−/− mice were exposed to saline or FAP every 4 days for a total of five exposures. The mice were then assessed for airway hyperresponsiveness to escalating doses of methacholine. Saline exposed C57BL/6 (dotted box) and Mindin−/− (shaded box) mice demonstrated no difference in response to methacholine. C57BL/6 mice exposed to FAP (closed box) had a significant increase in AHR as compared to saline controls. This effect was reduced in the Mindin −/− mice exposed to FAP (open box). (*P<0.05 between C57BL/6 saline and FAP exposed and C57BL/6 and Mindin−/− FAP exposed mice, N=6, representative of two experiments).