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. 2013 Mar 1;123(4):1580–1589. doi: 10.1172/JCI60083

Figure 6. STAT3 binds to the promoter region of ARG1 of MDSC.

Figure 6

ChIP assay demonstrated pSTAT3 binding to ARG1 promoter regions at 3 of the 6 potential binding sites (from a total of 12 sites matching the consensus sequences generated by Vista genomic program). The sequence of the human ARG1 promoter region with the 6 potential pSTAT3-binding sites is shown in Supplemental Table 2.