Figure 6. EpCAM^–/CD49e⁺/HLA-ABC⁺ cells form testicular tumors following transplantation into nude mice, but EpCAM^lo /CD49e^–/HLA-ABC^– cells do not form tumors.

(A and B) Unsorted spiked testicular cells and cells from fraction II (see Figure 5A) produced tumors in recipient mouse testes. (C) Cells from fraction IIIa (see Figure 5, A and B) that contained human spermatogonia colonizing the seminiferous tubule of nude mice (see Figure 5G) did not produce tumors.