Table 2.
Maternal, cord, and infant blood tacrolimus levels and breast milk levels
| Sample Type | Breast-Fed Infants (n=12) | Bottle-Fed Infants (n=3) | All | |||
|---|---|---|---|---|---|---|
| n | Median (Range) | n | Median (Range) | n | Median (Range) | |
| Gestation (wk) | 36 (24–39) | 35 (32–37) | 36 (24–39) | |||
| Birth weight (g) | 2450 (720–2910) | 2431 (1750–2822) | 2440 (720–2910) | |||
| Maternal blood at delivery (µg/L) | 7 | 6.2 (4.6–11.2) | 1 | 7.3 | 8 | 6.6 (4.6–11.2) |
| Maternal blood day ≥1 (µg/L) | 24 | 4.1 (1.3–7.0)a | 7 | 9.0 (4.9–16)a | 31 | 4.4 (1.3–16) |
| Infant cord blood (µg/L) | 6 | 4.6 (1.0–9.0) | 1 | 4.6 | 7 | 4.6 (1.0–9.0) |
| Infant blood day ≥1 (µg/L) | 24 | 1.3 (0.0–4.0) | 6 | 1.0 (0.0–2.3) | 30 | 1.1 (0.0–4.0) |
| Breast milk (µg/L) | 17 | 0.7 (0.1–1.6) | 5 | 1.3 (0.7–1.6) | 22 | 0.8 (0.1–1.6) |
a
P<0.001.