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. 2013 Jan 10;8(4):629–636. doi: 10.2215/CJN.08780812

Figure 2.

Figure 2.

High-performance liquid chromatography profiles of OPA-derivatized lyso-Gb3 extracted from human plasma. The peak identified as OPA-derivatized lyso-Gb3 is indicated by the arrow. (A) Case 1 (p.Y173X hemizygote, 128 nM lyso-Gb3); (B) 100 nM authentic lyso-Gb3 in normal plasma; (C) 50 nM authentic lyso-Gb3 in normal plasma; (D) normal plasma; (E) case 2 (p.E66Q hemizygote, 3.1 nM lyso-Gb3); (F) case 3 (p.E66Q hemizygote, 1.9 nM lyso-Gb3); (G) case 1’s elder sister (p.Y173X heterozygote, 6.9 nM lyso-Gb3); and (H) 10 nM authentic lyso-Gb3 in normal plasma. OPA, O-phthaldialdehyde; lyso-Gb3, globotriaosylsphingosine.