Table 3.

Sensitivity and specificity of plasma lyso-Gb3 screening for FD

	FD (+)	FD (−)	Total
Lyso-Gb3 (+)	1	2	3
Lyso-Gb3 (−)	0	33	33
Total	1	35	36
Sensitivity (%)	100
Specificity (%)		94.3

In total, we performed α-galactosidase A gene analysis for 36 male dialysis patients with low α-galactosidase A activity. We found one FD (+) patient with class 1 mutation (p.Yl73X) and 35 FD (−) patients consisting of 9 FD (−) patients with class 2 mutation (p.E66Q) and 26 FD (−) patients without a GLA mutation. The sensitivity was calculated by dividing the number of lyso-Gb3 (+) patients by the total number of total FD (+) patients. The specificity was calculated by dividing the number of lyso-Gb3 (−) patients by the number of total FD (−) patients. Lyso-Gb3, globotriaosylsphingosine; FD, Fabry disease; GLA, α-galactosidase A gene.