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High-throughput screen (HTS) campaign statistics. The graph shows scatter plots of the calculated Z′-scores (○) and signal-to-background (S/B, •) values of the NR2E3 primary screen. Three hundred fifteen plates were run in 7 different batches, comprising a total of 257 compound plates. The average Z′-factor and S/B ratio for the entire primary screening campaign were 0.89±0.01 and 2.45±0.12, respectively.
