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. Author manuscript; available in PMC: 2013 Apr 2.
Published in final edited form as: Cancer Res. 2007 Dec 15;67(24):11760–11768. doi: 10.1158/0008-5472.CAN-07-3233

Figure 6.

Figure 6

Distribution of full-length and cleaved galectin-3 in human breast cancer: A: DCIS; B: Infiltrating ductal carcinoma. In human DCIS (A), full-length galectin-3 is concentrated more towards the lumen of the duct, many cells towards the stromal end are devoid of the protein (mAb; arrow). The cleaved galectin-3 fragments (pAb) as well as MMP-9 could be seen in all cells. In infilterating ductal carcinoma (B), full-length galectin-3 is seen in ductules that maintained a normal morphology (arrow) and in some invasive cells (mAb); cleaved galectin-3 (pAb) and MMP-9 are seen in invasive cell clusters and stroma (arrows). Lower panels in A and B represent box in the upper panels. Bar: 50 micron (upper panels); 200 micron (lower panels).