Table 3.
USPIO dose | 1 × 106 cells | 5 × 105 cells | 2.5 × 105 cells |
---|---|---|---|
Full | 249 ± 102 | 135 ± 91 | 100 ± 64 |
Half | 134 ± 82 | 91 ± 76 | 45 ± 92 |
Unlabeled | 46 ± 58 | 25 ± 47 | 8 ± 53 |
| |||
Multiple comparisons | P < 0.001 | P = 0.007 | P = 0.008 |
| |||
Full versus unlabeled | P < 0.001 | P = 0.006 | P = 0.006 |
Full versus half | P = 0.034 | ns | ns |
Half versus unlabeled | ns | ns | ns |
The MRI intensities are mean pixel intensities (values between 0 and 4095) of a 20 mm2 region of interest in the center area of each phantom, supplied by the imaging software. Values are shown ± SD.
USPIO: ultrasmall super-paramagnetic iron-oxide. USPIO dose—full = 10 μg per 105 cells. half = 5 μg per 105 cells, ns: non-significant.