Figure 1.

Unadjusted quarterly rates of community-acquired pneumonia, osteoarthritis, chest pain, and urinary tract infection medical claims among users and nonusers of proton pump inhibitors. Unadjusted quarterly rates of each condition were calculated for those never filling a prescription for a PPI (termed nonusers of PPIs), users (defined as persons who filled at least one prescription for a PPI) during quarters in which a prescription was not filled, and users during quarters in which a prescription was filled. Rates were determined from ICD-9 codes in administrative data and are displayed at the quarterly level per 10,000 persons. 95 % confidence intervals reported in graph.