Table 1. Effect of different extract fractions of M. annua Linn leaves and reference ointment on % wound contraction and epithelialization period of excision wound in rats (Mean±SD) (n=6).
Groups | Percent wound contraction |
Epithelialization period | |||||||||
2 day | 4 day | 6 day | 8 day | 10 day | 12 day | 14 day | 16 day | 18 day | 20 day | ||
Control | 7.13 ±0.83 | 15.06±0.56 | 25.61±1.32 | 34.04±0.97 | 41.14±1.57 | 50.22±1.88 | 66.71±0.58 | 78.93±2.13 | 84.62±1.48 | 90.37±2.07 | 24 |
MAF A | 10.62±0.79 | 28.33±1.62 | 41.52±1.55 | 54.12±1.39 | 69.73±2.44 | 74.45±0.76 | 80.17±1.88 | 88.81±1.07 | 92.43±2.47 | 100.00 | 20 |
MAF B | 18.41±0.38 | 25.73±0.57 | 36.51±1.22 | 49.05±2.75 | 56.67±1.46 | 72.44±0.76 | 86.34±1.57 | 93.53±0.89 | 97.52±1.58 | 100.00 | 20 |
MAF C | 10.75±1.52 | 26.50±1.58 | 35.49±2.41 | 51.87±0.87 | 67.48±1.74 | 79.68±1.88 | 82.14±0.98 | 90.31±2.32 | 100.00 | - | 18 |
Reference ointment | 11.37±1.30 | 25.65±0.87 | 40.82±1.05 | 56.44±1.54 | 67.11±0.86 | 78.59±1.76 | 84.42±1.72 | 97.75±1.72 | 100.00 | - | 18 |
P<0.01 as compared with control group.