(A) Comparison of cumulative elution from low and high molecular weight PLGA (LMW and HMW, respectively) at ultrasonication power settings #1, 3, and 5. HMW-PLGA exhibits greater cumulative elution. (B) Comparison of percent total elution from low and high molecular weight (LMW and HMW, respectively) PLGA at ultrasonication power settings #1, 3, and 5. Note initial burst phenomenon is more prevalent at lower ultrasonication powers and with LMW-PLGA.