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. Author manuscript; available in PMC: 2013 Nov 13.
Published in final edited form as: Chem Sci. 2012 Nov 13;4(2):650–654. doi: 10.1039/C2SC21617E

Table 2.

Substrate scope: α-imino ester.

graphic file with name nihms421032t2.jpg

entry graphic file with name nihms421032t3.jpg yielda
(%)
eeb
(%)
entry graphic file with name nihms421032t3.jpg yielda
(%)
eeb
(%)
1 graphic file with name nihms421032t4.jpg 90 91 11d graphic file with name nihms421032t5.jpg 86 90
2 graphic file with name nihms421032t6.jpg 91 91 12 graphic file with name nihms421032t7.jpg 72 90
3c graphic file with name nihms421032t8.jpg 83 88 13 graphic file with name nihms421032t9.jpg 87 94
4c graphic file with name nihms421032t10.jpg 82 92 14 graphic file with name nihms421032t11.jpg 89 93
5c graphic file with name nihms421032t12.jpg 78 88 15 graphic file with name nihms421032t13.jpg 82 92
6 graphic file with name nihms421032t14.jpg 87 93 15d graphic file with name nihms421032t15.jpg 76 92
7 graphic file with name nihms421032t16.jpg 91 95 17c graphic file with name nihms421032t17.jpg 84 93
8 graphic file with name nihms421032t18.jpg 89 92 18 graphic file with name nihms421032t19.jpg 90 90
9 graphic file with name nihms421032t20.jpg 70 96
10 graphic file with name nihms421032t21.jpg 80 96 19 graphic file with name nihms421032t22.jpg 33 44
a

Isolated yield.

b

Determined by SFC using chiral stationary phase.

c

6 mol % each AgOAc and (S)-16 were employed.

d

6 mol % each AgOAc and (S)-16 were employed at 0.1 M reaction concentration.