Table 5.

Odds ratios for the development of acute kidney injury when CK and/or sMb are above their cutoff values (based on ROC curves)

	Model corrected for known risk factors*
		95% confidence interval
	OR	Lower	Upper	p value**
CK > 773, sMb ≤ 368	1.06	0.45	2.27	0.8818
CK ≤ 773, sMb > 368	4.29	2.71	6.8	<0.0001
CK > 773, sMb > 368	5.11	3.03	8.63	<0.0001

*Risk factors at baseline: mean blood pressure, creatinine, CK, sMb, uMb, PaO₂, lactate, osmolarity, SOFA, use of loop diuretics, sepsis, hours of surgery > 6, inotropic index, mechanical ventilation, trauma and muscle ischemia.

**p value compared with the reference group CK ≤ 773 U/l and sMb ≤ 368 μg/l.