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. 2013 Mar 22;14:84. doi: 10.1186/1745-6215-14-84

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Copyright © 2013 Drozdov et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Individualized antibiotic guidance by PCT and pyuria. The algorithm for diagnostic purposes is shown. If there is any concern about microbiologic resistance, therapy extension is considered. For proven microbiologic resistance therapy is adjusted. Remaining antibiotic treatment after patient discharge is guided by last PCT value to result in total antibiotic duration in analogy to outpatient treatment. Abx: antibiotics; GFR: estimated glomerular filtration rate with MDRD formula; ICU: intensive care unit; NSAIDs: nonsteroidal anti-inflammatory drugs; PCT: procalcitonin; TMP-SMX: trimethoprim-sulfamethoxazole; UST: urinalysis; UTI: urinary tract infection.