Table 2. Antimicrobial activity of L/D-Phes.
Microorganism | MIC (µM)a | |||||
L-Phes | D-Phes | Mg | DS01 | Amp. | Chloram. | |
S. aureus ATCC 29313 | 65.5 | 32.7 | ND | 26,5 | <11 | ND |
E. coli ATCC 25922 | 65.5 | 65.5 | 79 | 6,6 | 46 | 25 |
P. aeruginosa ATCC 27853 | >130 | 130 | 157.8 | NT | 25 | 25 |
X. axonopodis pv glycines ISBF 327 a | 32.7 | 4.1 | 13 | <1.42 | ND | ND |
MIC -minimal peptide concentrations required for total inhibition of cell growth.
ND - antimicrobial activity not detectable;
Phytophatogenic bacteria; Amp and Chloram- ampicillin and chloramphenicol; Mg and DS01 - control peptides Magainin (Zasloff, et al and Brand, et al).