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. 2007 Mar;3(1):20–30.

Table 6.

Application of the proposed methods for the determination of the studied drugs in their raw materials

Compound Proposed methods
Reference methods (30, 31)
Amount taken (μg/ml) Amount found (μg/ml) Recovery (%) Amount taken (μg/ml) Recovery (%)

At 610 nm
Acarbose 4.0 3.978 99.45
5.0 4.919 98.38
10.0 10.135 101.35
15.0 15.039 100.26
20.0 19.926 99.63
x ± S.D. 99.81 ± 1.093 99.20 ± 0.400
t 0.906 (2.447)a
F 7.47 (19.25)
Miglitol 1.0 1.021 102.10
2.0 2.015 100.75 60.0 101.00
4.0 3.937 98.43 80.0 98.50
6.0 6.019 100.32 100.0 100.61
8.0 8.000 100.00
10.0 10.009 100.09
x ± S.D. 100.28 ± 1.189 100.04 ± 1.350
t 0.274 (2.365)a
F 1.29 (19.30)
At 525 nm
Acarbose 4.0 4.039 100.98
5.0 4.950 99.00
100 10.027 100.27
15.0 14.971 99.81
20.0 20.013 100.06
x ± S.D. 100.02 ± 0.719 99.20 ± 0.400
t 1.779 (2.447)a
F 3.23 (19.25)
Miglitol 2.0 1.967 98.35
4.0 4.045 101.13 60.0 101.00
6.0 6.067 101.12 80.0 98.50
8.0 8.052 100.65 100.0 100.61
10.0 9.911 99.11
x ± S.D. 100.07 ± 1.270 100.04 ± 1.350
t 0.032 (2.447)a
F 1.13 (19.25)

Each result is the average of three separate determinations.

a

Figures in parentheses are the tabulated t and F values, respectively at p=0.05 (32).