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. 2007 Mar;3(1):20–30.

Table 7.

Application of the proposed methods for the determination of the studied drugs in pharmaceutical preparations

Pharmaceutical preparations Proposed methods
Reference methods
Amount taken (μg/ml) Amount found (μg/ml) Recovery (%) Taken (μg/ml) Recovery (%)

At 610 nm
  Glucobay 50 tabletsa 5.0 5.008 100.16
  (Acarbose, 50 mg/tablet) 10.0 10.091 100.91
15.0 15.218 101.45
x ± S.D. 100.84 ± 0.648 100.400 ± 0.400
t 1.002 (2.776)c
F 2.62 (19.00)
  Glyset 50 mg tabletsb 2.0 1.978 98.90 60.0 97.26
  (Miglitol, 50 mg/tablet) 4.0 4.025 100.63 80.0 98.71
8.0 8.099 101.24 100.0 99.66
x ± S.D. 100.26 ± 1.214 98.54 ± 1.208
t 1.740 (2.776)c
F 1.01 (19.00)
At 525 nm
  Glucobay 50 tablets 4.0 4.044 101.10
  (Acarbose, 50 mg/tablet) 10.0 10.062 100.62
20.0 20.220 101.10
x ± S.D. 100.94 ± 0.277 100.400 ± 0.400
t 1.923 (2.776)c
F 2.086 (19.00)
  Glyset 50 mg tablets 2.0 1.987 99.35 60.0 97.26
  (Miglitol, 50 mg/tablet) 4.0 4.070 101.75 80.0 98.71
8.0 8.036 100.45 100.0 99.66
x ± S.D. 100.52 ± 1.201 98.54 ± 1.208
t 2.014 (2.776)c
F 1.01 (19.00)

Each result is the average of three separate determinations.

a

Product of Alkan Pharma S.A.E., Egypt under licence of Bayer-Leverkusen, Germany, Egypt;

b

Product of Sigma Pharma-ceutical industries, Egypt;

c

Figures in parentheses are the tabulated t and F values, respectively at p=0.05 (32).