Table 4.

Average Admission (A) and monthly values for Lipids: Cholesterol (CHOL), Triglycerides (TRGL), High Density Lipoproteins (HDL) and Low Density Lipoproteins (LDL) and Minerals: Calcium (Ca), Phosphorus (P) and Iron (Fe) levels at five sampling points (Month Model)^a and Placebo (P) versus Maca-GO (M) contrast (Treatment Model) for two application sequences in a crossover design: A[PP × MM] and A[MM × PP] (n=11 in each group) during four months study

Measurement	Treatment	Admission (A)	End of Month 1	End of Month 2	End of Month 3	End of Month 4	SEDb	Placebo	Maca	SED	Pc
Lipids
CHOL (mg/100ml)	APPMM	215.1	222.9	233.7	232.3	230.6	9.2	228.3	231.6	6.6	ns
	AMMPP	221.3	220.4	226.6	235	222.4	8.47	228.7	223.5	6.2	ns
	SED		21.1	21.1	21.2	21.7		20.2	20.2
	P		ns	ns	ns	ns		ns	ns
TRGL (mg/100ml)	APPMM	147.2	134.7	166.1	160.1	176.7	24.4	150.4	166.9	17.1	ns
	AMMPP	167	160.4	134.3	140.6	161.3	22.52	151	147.3	16.1	ns
	SED		40.7	40.7	41.1	42.9		37.8	37.9
	P		ns	ns	ns	ns		ns	ns
HDL (mg/100ml)	APPMM	59.41	66.73	67.72	67.82	70.07	3.19	67.23	68.75	2.27	ns
	AMMPP	64.66	64.77	66.2	68.29	61.25	2.94	64.77	65.49	2.15	ns
	SED		7.75	7.75	7.79	7.95		7.49	7.5
	P		ns	ns	ns	ns		ns	ns
LDL (mg/100ml)	APPMM	138	150.1	142.8	168	169.3	10	146.8	168.6	6.8	<0.01
	AMMPP	148.6	152.8	148	163.9	154.5	8.37	159.2	150.4	5.9	ns
	SED		20.7	21	21.2	21.6		20	20.1
	P		ns	ns	ns	ns		ns	ns
Minerals
Ca (mEq/L)	APPMM	4.46	4.73	5.03	4.8	4.714	0.085	4.88	4.765	0.075	ns
	AMMPP	4.49	4.69 B	4.95 A	4.73 B	4.63 B	0.085*	4.68	4.82	0.071	ns
	SED		0.119	0.119	0.119	0.119		0.104	0.104
	P		ns	ns	ns	ns		ns	ns
P (mg/100ml)	APPMM	3.22	3	3.16	3.14	3.143	0.203	3.08	3.141	0.157	ns
	AMMPP	3.27	3.66	3.19	3.62	3.28	0.203	3.45	3.425	0.157	ns
	SED		0.258	0.258	0.258	0.258		0.217	0.217
	P		<0.05	ns	ns	ns		ns	ns
Fe (mcg/100ml)	APPMM	69.27	82.08	80.78	81.39	82.23	10.51	81.43	81.74	8.02	ns
	AMMPP	85.45	120.1	101.97	97.49	75.38	10.51	86.43	111.04	8.02	<0.01
	SED		11.32	11.32	11.32	11.32		8.63	8.63
	P		<0.01	ns	ns	ns		ns	<0.01

^aFor explanation see Table 1;

^bSED, Standard error of differences;

^*existence of significant differences between monthly measurements within the same treatment sequence group. Values marked with unlike capital letters are considered statistically significant at P<0.05.

^cP, Probabilities of significance.ns, not significant at P>0.05; <0.05, significance at 5% probability level; <0.01, significance at 1% probability level; <0.001, significance at 0.1% probability level.