. 2006 Dec;2(4):360–374.

Table 6.

TRIAL I. Monthly changes in values of individual symptoms determined according to Greene’s Menopausal Score (GMS) for APMM sequence treatment (n=55) in early-postmenopausal women recorded between Admission (A), and three monthly sampling points (Month Model)^a with one month Placebo (P) followed by two months Maca-GO (M) contrast (Treatment Model)1 according to the sequence applied in Trial I

Individual Menopausal Symptoms’ Scores according to Greene
Symptom	Admission A	After Month 1 (P)	After Month 2 (M)	After Month 3 (M)	±SED^b	P^c	Placebo	Maca	±SED^b	P^c

Abnormally-fast heart rate	0.66	0.45	0.35	0.28	0.149	0.094	0.455	0.315	0.118	0.240
Nervousness	1.51	1.68	1.00	0.76	0.200	<0.001	1.682	0.879	0.169	<0.001
Difficulty falling asleep	1.15	1.12	0.77	0.52	0.212	0.009	1.121	0.646	0.169	0.006
Excessive alertness	1.33	1.33	1.00	0.55	0.175	<0.001	1.333	0.776	0.147	<0.001
Sudden feeling of anxiety	0.82	0.70	0.45	0.45	0.193	0.145	0.697	0.450	0.169	0.147
Difficulty concentrating	0.97	1.09	0.94	0.41	0.182	0.002	1.091	0.675	0.153	0.008
Feeling of tiredness/lack of energy	1.39	1.54	1.32	0.72	0.205	<0.001	1.545	1.023	0.173	0.003
Lack of interest	0.36	0.33	0.26	0.21	0.129	0.612	0.333	0.233	0.111	0.037
Unhappy/depressed	1.00	0.94	0.74	0.45	0.201	0.030	0.939	0.595	0.174	0.050
Excessive crying	0.45	0.27	0.23	0.24	0.129	0.263	0.273	0.234	0.109	0.721
Irritability	1.27	1.15	0.84	0.65	0.189	0.005	1.152	0.747	0.165	0.016
Loss of consciousness	0.61	0.88	0.45	0.41	0.170	0.030	0.879	0.433	0.147	0.003
Nervous tension	0.72	0.59	0.52	0.41	0.156	0.238	0.591	0.465	0.133	0.345
Numbness/“pins & needles”	0.67	0.61	0.45	0.31	0.183	0.207	0.606	0.381	0.153	0.144
Headaches	0.97	0.85	0.58	0.34	0.206	0.014	0.848	0.463	0.167	0.023
Muscle and joint aches and pains	1.24	1.18	0.97	0.62	0.224	0.027	1.182	0.794	0.193	0.047
Loss of feeling in feet & hands	0.45	0.36	0.19	0.24	0.148	0.284	0.364	0.217	0.123	0.239
Difficulty breathing	0.27	0.12	0.16	0.10	0.097	0.303	0.121	0.132	0.073	0.879
Hot flushes	1.73	1.73	1.10	0.52	0.257	<0.001	1.727	0.807	0.210	<0.001
Excessive night sweating	1.45	1.39	1.06	0.48	0.253	<0.001	1.394	0.774	0.203	0.003
Loss of interest in sex life	1.06	1.12	0.84	0.60	0.200	0.036	1.121	0.712	0.173	0.020
TOTAL GMS	20.09	19.45	13.36	8.15	1.869	<0.001	19.45	10.76	0.16	<0.001

For explanation see Table 1;

SED, Standard error of differences;

P, Probabilities of significance. ns, not significant at P>0.05; P<0.05, significance at 5% probability level; P<0.01, significance at 1% probability level; P<0.001, significance at 0.1% probability level.