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. 2007 Sep;3(3):199–205.

Figure 5.

Figure 5

Protection with VP1-mSurvivin VLPs in a mouse melanoma model. Four C57BL/6 mice per group were immunized twice with VP1-mSurvivin VLPs in 7 days intervals and were charged 7 days later s.c. with 105 MO5 melanoma tumor cells. One group was mock-immunized with PBS (open squares), the next with VLPs lacking the tumor antigen (solid triangles) and the last group with VP1-mSurvivin VLPs (solid diamonds). Immunization with antigen-presenting VLPs significantly increased the survival rate of the animals.