Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2007 Sep;3(3):199–205.

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Thomas Schumacher et al. Licensee Master Publishing Group

This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PMC Copyright notice

Therapy and tumor growth with VP1-mSurvivin pentamers in a mouse melanoma model. Five C57BL/6 mice per group were charged s.c. with 10⁵ B16-F10 melanoma tumor cells and subsequently immunized twice with VP1-mSurvivin pentamers after 4 and 8 days. One group was mock-immunized with PBS (open squares), the next with pentamers lacking the tumor antigen (solid triangles) and the last group with VP1-mSurvivin pentamers (solid diamonds). (A) Immunization with antigen-presenting pentamers significantly increased the survival rate of the animals. (B) As expected, tumor growth was clearly delayed by the immunization with antigen-presenting pentamers.