Table 2.
Inflammatory markers time course in plasma of patient undergoing surgery under Cardiopulmonary Bypass (CPB)
| Pre-CPB | Per-CPB | Post-ACU | |
|---|---|---|---|
| MCP-1 (pg/mL) | 355.92 ± 55.88 | 1196.23 ± 218.25a | 1238.52 ± 165.67b |
| P-selectin (ng/mL) | 103.05 ± 12.97 | 121.37 ± 13.08a | 1140.09 ± 12.98b |
| t-PA (pg/mL) | 1331.45 ± 168.78 | 3788.32 ± 281.85a | 4037..83 ± 490.52b |
| IL 6 (pg/mL) | 18.09 ± 7.44 | 75.24 ± 17.88a | 119.61 ± 25.26b |
| IL 8 (pg/mL) | 19.80 ±7.46 | 254.26 ± 126.23a | 305.85 ± 166.15b |
| IL 10 (pg/mL) | 43.52 ± 24.07 | 475.95 ± 215.67a | 319.63 ± 97.78b |
| VCAM 1 (pg/mL) | 474.34 ± 182.36 | 541.30 ± 58.59 | 500.33 ± 30.79 |
| CD40 L (ng/mL) | 914.18 ± 100.39 | 1084.63 ± 93.68 | 1062.33 ± 112.89 |
ACU, Aortic Cross Unclamping; IL, interleukin; MCP-1, Monocyte Chemoattractant Protein 1; t-PA, tissular Plasminogen Activator; VCAM-1, Vascular Cells Adhesion Molecule 1; CD40 L, CD40 Ligand.
a
per-CPB vs pre-CPB, p<0.05;
b
post-ACU vs pre-CPB, p<0.05.