Table 2.
Accuracy and precision of the HPLC method for simultaneous determination of ceftriaxone sodium and sulbactam sodium
| Drugs | Accuracy |
Precision |
|||
|---|---|---|---|---|---|
| Mean recovery ± SD | RSD (%, n=9) | 75% | 100% | 125% label claim | |
| Ceftriaxone | 100.88 ± 0.31 | 0.53 | 0.34 | 0.29 | 0.31 |
| Sulbactam | 100.54 ± 0.53 | 0.31 | 0.39 | 0.15 | 0.44 |
The chromatographic conditions used were: ODS Hypersil C-18 Column, mobile phase of acetonitrile and 0.005N TBAH (30:70), flow rate of 1.5 ml/min, detection wavelength of 220 nm, room temperature 25°C.