Table 3.
Summary of accuracy and precision results of the proposed method in pharmaceutical formulations
| Proposed methods | Amount (μg/ml) |
RSD (%) | REC. (%) | SAEb | C.L.c | |
|---|---|---|---|---|---|---|
| Taken | Found ± SDa | |||||
| Intra day assay | ||||||
| Gabanext-75 | 2.00 | 2.000±0.018 | 0.891 | 100.000 | 0.0070 | 0.0221 |
| Gabanext-75 | 3.50 | 3.498±0.017 | 0.477 | 99.943 | 0.0075 | 0.0201 |
| Gabanext-75 | 5.00 | 4.999±0.017 | 0.333 | 99.999 | 0.0074 | 0.0206 |
| Pregalin-75 | 2.00 | 1.999±0.006 | 0.258 | 99.980 | 0.0023 | 0.0064 |
| Pregalin-75 | 3.50 | 3.498±0.017 | 0.476 | 99.943 | 0.0074 | 0.0207 |
| Pregalin-75 | 5.00 | 4.996±0.032 | 0.630 | 99.920 | 0.0141 | 0.0391 |
| Neugaba-75 | 2.00 | 1.999±0.011 | 0.569 | 99.970 | 0.0051 | 0.0142 |
| Neugaba-75 | 3.50 | 3.502±0.031 | 0.899 | 100.057 | 0.0141 | 0.0391 |
| Neugaba-75 | 5.00 | 5.004±0.023 | 0.454 | 100.080 | 0.0102 | 0.0282 |
| Maxgalin-75 | 2.00 | 1.999±0.011 | 0.569 | 99.970 | 0.0051 | 0.0142 |
| Maxgalin-75 | 3.50 | 3.506±0.026 | 0.741 | 100.171 | 0.0117 | 0.0322 |
| Maxgalin-75 | 5.00 | 4.996±0.020 | 0.399 | 99.940 | 0.0089 | 0.0247 |
| Mahagaba-75 | 2.00 | 1.999±0.019 | 0.968 | 99.924 | 0.0087 | 0.0240 |
| Mahagaba-75 | 3.50 | 3.498±0.030 | 0.845 | 99.943 | 0.0132 | 0.0367 |
| Mahagaba-75 | 5.00 | 5.000±0.022 | 0.436 | 100.000 | 0.0098 | 0.0271 |
| Inter day assay | ||||||
| Gabanext-75 | 2.00 | 1.996±0.011 | 0.547 | 99.801 | 0.0049 | 0.0136 |
| Gabanext-75 | 3.50 | 3.494±0.018 | 0.510 | 99.829 | 0.0079 | 0.0221 |
| Gabanext-75 | 5.00 | 4.996±0.024 | 0.488 | 99.920 | 0.0109 | 0.0303 |
| Pregalin-75 | 2.00 | 1.999±0.011 | 0.569 | 99.970 | 0.0051 | 0.0142 |
| Pregalin-75 | 3.50 | 3.499±0.012 | 0.341 | 99.967 | 0.0053 | 0.0172 |
| Pregalin-75 | 5.00 | 4.997±0.010 | 0.203 | 99.940 | 0.0045 | 0.0125 |
| Neugaba-75 | 2.00 | 2.004±0.016 | 0.832 | 100.199 | 0.0075 | 0.0020 |
| Neugaba-75 | 3.50 | 3.498±0.012 | 0.331 | 99.943 | 0.0052 | 0.0144 |
| Neugaba-75 | 5.00 | 4.997±0.013 | 0.264 | 99.940 | 0.0059 | 0.0164 |
| Maxgalin-75 | 2.00 | 2.000±0.022 | 1.136 | 99.999 | 0.0102 | 0.0282 |
| Maxgalin-75 | 3.50 | 3.498±0.017 | 0.476 | 99.943 | 0.0074 | 0.0207 |
| Maxgalin-75 | 5.00 | 4.997±0.013 | 0.264 | 99.940 | 0.0059 | 0.0164 |
| Mahagaba-75 | 2.00 | 2.000±0.018 | 0.891 | 100.000 | 0.0070 | 0.0221 |
| Mahagaba-75 | 3.50 | 3.502±0.031 | 0.899 | 100.057 | 0.0141 | 0.0391 |
| Mahagaba-75 | 5.00 | 4.997±0.010 | 0.203 | 99.940 | 0.0045 | 0.0125 |
a
Mean for 5 independent analyses;
b
SAE, standard analytical error;
c
C.L., confidence limit at 95% confidence level and 4 degrees of freedom (t=2.776).