Table 3.

Application of the proposed method and comparison method for the simultaneous determination of NF and TZ in synthetic mixture in the ratio of 2:3 respectively

Drug determined	Proposed method			Reference method (34, 38)
	Amount taken (μg/mL)		% Found	Amount taken (μg/mL)	% Found
	NF	TZ
Norfloxacin	6	9	100.00	6	98.75
	8	12	100.50	8	100.28
	10	15	101.00	10	99.33
	% R ± SD = 100.50 ± 0.50			% R ± SD = 99.45 ± 0.77
	t-value = 2.03 (2.78)
	F-value = 2.39 (19)
Tinidazole	6	9	99.50	9	99.39
	8	12	100.17	12	99.08
	10	15	99.87	15	100.12
	% R ± SD = 99.85 ± 0.34			% R ± SD = 99.53 ± 0.53
	t-value = 1.64 (2.78)
	F-value = 2.53 (19)

Figures between brackets are the tabulated t and F-values at (P=0.05). In each of proposed and reference method, three samples of NF and TZ synthetic mixture were repeated.