Table 5.
Assay results for the determination of NF and TZ in Conaz® tablet by the proposed method and comparison method
| Drug determined | Proposed method |
Reference method (34, 38) |
||
|---|---|---|---|---|
| Amount taken (μg/mL) | Amount found (μg/mL) | % Found | % Found | |
| Norfloxacin | 6 | 6.01 | 100.21 | 98.13 |
| 8 | 7.96 | 99.50 | 101.21 | |
| 10 | 10.03 | 100.30 | 98.20 | |
| %R ± SD = 100.00 ± 0.44 | %R ± SD = 99.18 ± 1.75 | |||
| t-value = 1.95(2.78) | ||||
| F-value = 16.10 (19) | ||||
| Tinidazole | 9 | 9.02 | 100.17 | 101.43 |
| 12 | 11.97 | 99.79 | 102.14 | |
| 15 | 14.98 | 99.87 | 101.35 | |
| % R ± SD = 99.94 ± 0.20 | % R ± SD = 101.64 ± 0.43 | |||
| t-value = 2.42 (2.78) | ||||
| F-value = 4.73 (19) | ||||
Figures between brackets are the tabulated t and F-values at (P=0.05). Each result is the mean recovery of three separate determinations. In each of proposed and reference method, three samples were repeated. Batch No. 916 9019.