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Time course of the edema ratio after topical application of 1% diclofenac patch or other NSAID patch on the carrageenan-induced hind footpad paw edema in rats. Data are expressed as the mean ±S.D. of 10 animals. **p<0.01: 1% diclofenac patch: significantly different from the inflammatory control group; #p<0.05: 1% diclofenac patch: significantly different from the 3.75% indomethacin patch group (Dunnett’s test).
