Table 4.
Genotype distribution of the PLD1 polymorphisms in non-small cell lung cancer and controls
| SNP | Group | Genotypes of PLD1 polymorphisms |
|||
|---|---|---|---|---|---|
| W/S (%)a | W/V (%)a | V/V (%)a | P-value (p<) | ||
| 2660 G→T | Lung cancer | 192 (91.0) | 17 (8.1) | 2 (0.9) | 0.013 |
| control | 200 (97.6) | 5 (2.4) | 0 (0.0) | ||
| 2690 A→T | Lung cancer | 190 (90.0) | 19 (9.0) | 2 (0.9) | 0.092 |
| control | 195 (95.1) | 10 (4.9) | 0 (0.0) | ||
| 2698 A→C | Lung cancer | 50 (23.7) | 120 (56.9) | 41 (19.4) | 0.001 |
| control | 113 (55.1) | 69 (33.7) | 23 (11.2) | ||
| 2708 A→C | Lung cancer | 190 (90.0) | 20 (9.5) | 1 (0.5) | 0.612 |
| control | 186 (90.7) | 19 (9.3) | 0 (0.0) | ||
| 2744 A→C | Lung cancer | 184 (87.2) | 27 (12.8) | 0 (0.0) | 0.005 |
| control | 195 (95.1) | 10 (4.9) | 0 (0.0) | ||
| 2756 A→C | Lung cancer | 184 (87.2) | 27 (12.8) | 0 (0.0) | 0.005 |
| control | 195 (95.1) | 10 (4.9) | 0 (0.0) | ||
p-values for genotypes was obtained from Pearson’s χ2-test.
a
W means wild-type allele and V means variant allele of each SNP.