Table 1. Clinical data and inflammatory parameters of the four study groups (median [interquartile range]).
| HNP(n = 29) | HP(n = 58) | ANP(n = 38) | AP(n = 15) | |
| Female / male | 19 / 10 | – | 27 / 11 | |
| Age (years) | 36 [30–52] | 31 [28]–[35] | 39 [32–58]b | 29.5 [26]–[32] c |
| Gestational age at sampling (weeks) | – | 36 [34]–[38] | – | 27.5 [24–33.5]b |
| Gestational age at delivery (weeks) | – | 39 [38]–[40] | – | 38 [38]–[39] |
| Fetal birth weight (grams) | – | 3255 [3090–3745] | – | 3320 [3000–4000] |
| FEV1 (% of predicted) | – | – | 89.0 [83.5–98.0] | 96.0 [82.0–108.0] |
| PEF (% of predicted) | – | – | 90.5 [77.5–100.0] | 89.0 [75.0–107.0] |
| Raw (% of predicted) | – | – | 150 [92–179] | 105 [84–127] |
| ACT total score | – | – | 21.5 [17.5–24.0] | 22.0 [18.5–25.0] |
| Daily dose of ICS (beclomethasone equivalent, μg) | – | – | 1000 [800–1000] | 1000 [375-1000] |
| CRP (mg/L) | 2.50 [1.00–3.90] | 3.85 [2.08–6.53] | 3.00 [3.00–5.00] | 7.00 [3.00–9.00]a |
| suPAR (ng/mL) | 2.60 [1.82–3.49] | 2.01 [1.81–2.38]a | 2.84 [2.33–3.72]b | 2.39 [2.07–2.69]c |
| IL-6 (pg/mL) | 1.50 [1.50–1.70] | 1.50 [1.50–2.18] | 1.64 [1.50–3.36] | 1.82 [1.50–3.43] |
HNP – healthy non-pregnant; HP – healthy pregnant; ANP – asthmatic non-pregnant; AP – asthmatic pregnant; FEV1 – forced expiratory volume in 1 second; PEF – peak expiratory flow rate; Raw – airway resistance; ACT – asthma control test; ICS – inhaled corticosteroid; CRP – C-reactive protein; suPAR – soluble urokinase plasminogen activator receptor; IL-6 – interleukin 6; a p < 0.05 vs. HNP, b p < 0.05 vs. HP, c p < 0.05 vs. ANP.