Table 2. KI67 levels in mPIN lesions.
Genotype | Grade | Hormone Treatment | Aging (10 months) |
WT | Low | - | - |
High | NL | NL | |
TgPim1 | Low | - | - |
High | +++ | NL | |
PTEN-Het | Low | - | ++ |
High | +++ | - | |
TgPim1;PTEN-Het | Low | - | NA |
High | ++ | + |
Low grade: mPIN I and mPIN II. High grade: mPIN III and mPIN IV. In yellow conditions in which senescence markers were observed. NL: No lesions observed; NA: Not assessed.