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. 2013 Apr 2;8(4):e60277. doi: 10.1371/journal.pone.0060277

Table 2. KI67 levels in mPIN lesions.

Genotype Grade Hormone Treatment Aging (10 months)
WT Low - -
High NL NL
TgPim1 Low - -
High +++ NL
PTEN-Het Low - ++
High +++ -
TgPim1;PTEN-Het Low - NA
High ++ +

Low grade: mPIN I and mPIN II. High grade: mPIN III and mPIN IV. In yellow conditions in which senescence markers were observed. NL: No lesions observed; NA: Not assessed.