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. 2013 Apr 2;8(4):e60151. doi: 10.1371/journal.pone.0060151

Table 5. Ethnic differences of SNP (c.309 T>G) in the MDM2 gene among lung cancer cases.

Ethnicity Country Sample size T/T (%) T/G (%) G/G (%) Allele frequency (309 G) Reference
African-American USA 133 110 (83.3) 20 (15.2) 2 (1.5) 9.1% [36]
Caucasian USA 1787 702 (39.3) 802 (44.9) 283 (15.8) 38.3% [35]
Caucasian USA 1026 419 (40.8) 472 (46.2) 135 (13.2) 36.2% [34]
Caucasian Norway 341 130 (38.1) 156 (45.7) 55 (45.7) 39.0% [37]
Caucasian USA 371 150 (40.4) 167 (45.0) 54 (14.6) 37.1% [36]
Asian China 717 166 (52.0) 373 (52.0) 178 (24.8) 50.8% [36]
Asian China 1106 249 (22.5) 561 (50.7) 296 (26.8) 52.1% [38]
Asian Korea 582 113 (19.4) 280 (48.1) 189 (32.5) 56.5% [39]
Asian Japan 377 68 (18.0) 183 (48.5) 126 (33.4) 57.7% [30] *
Asian Japan 383 82 (21.4) 170 (44.4) 131 (34.2) 56.4% This study
*

Squamous cell carcinoma.