Table 5. Ethnic differences of SNP (c.309 T>G) in the MDM2 gene among lung cancer cases.
Ethnicity | Country | Sample size | T/T (%) | T/G (%) | G/G (%) | Allele frequency (309 G) | Reference |
African-American | USA | 133 | 110 (83.3) | 20 (15.2) | 2 (1.5) | 9.1% | [36] |
Caucasian | USA | 1787 | 702 (39.3) | 802 (44.9) | 283 (15.8) | 38.3% | [35] |
Caucasian | USA | 1026 | 419 (40.8) | 472 (46.2) | 135 (13.2) | 36.2% | [34] |
Caucasian | Norway | 341 | 130 (38.1) | 156 (45.7) | 55 (45.7) | 39.0% | [37] |
Caucasian | USA | 371 | 150 (40.4) | 167 (45.0) | 54 (14.6) | 37.1% | [36] |
Asian | China | 717 | 166 (52.0) | 373 (52.0) | 178 (24.8) | 50.8% | [36] |
Asian | China | 1106 | 249 (22.5) | 561 (50.7) | 296 (26.8) | 52.1% | [38] |
Asian | Korea | 582 | 113 (19.4) | 280 (48.1) | 189 (32.5) | 56.5% | [39] |
Asian | Japan | 377 | 68 (18.0) | 183 (48.5) | 126 (33.4) | 57.7% | [30] * |
Asian | Japan | 383 | 82 (21.4) | 170 (44.4) | 131 (34.2) | 56.4% | This study |
Squamous cell carcinoma.