Figure 4. Effects of inhibiting CPT1 by etomoxir on LA-induced increase in [Ca²⁺]i in rat β-cells.

A: 10 min LA-stimulated increase in [Ca²⁺]i after etomoxir treatment (0.1 mM for 10 min). B: the statistical results of the maximal Ca²⁺ levels in the first phase and in the second phase. ** means P<0.01 vs basal level. C and D: The mean Ca²⁺ changes in the first phase and in the second phase. There is no difference between LA and LA after etomoxir treatment (n = 6 for etomoxir).