Figure 6. Effects of depletion of intracellular Ca2+ stores by thapsigargin treatment on increase in [Ca2+]i in rat β-cells induced by GW9508, 2-min linoleic acid (LA) and 10-min LA.
A–C: Increase in [Ca2+]i in rat β-cells induced by GW9508, 2-min LA and 10-min LA, respectively. D: The mean Ca2+ changes in the first phase. ** means P<0.01 vs control group. E: The mean Ca2+ changes in the second phase. ** means P<0.01 vs control group (n = 8 for each group with thapsigargin treatment).