Table 2.

Updated Integrated Model Parameter Values^a

Name	Definition	Value
XCU	CU activity	1.5 nmol/min/mg
$K_{Ca}^{CU}$	Ca2+ binding constant for CU	3.69 μM
XRaM	RaM activity	0.25 nmol/min/mg
XNCE	NCE activity	0.5056 nmol/min/mg
$K_{Na}^{\mathit{NCE}}$	Na+ binding constant for NCE	2 mM
$K_{Ca}^{\mathit{NCE}}$	Ca2+ binding constant for NCE	110 nM
$n_H^{\mathit{NCE}}$	NCE H+ dependence	3
XCHE	CHE activity	4.0×1019 nmol/min/mg/M3
[BH]tot	Total mitochondrial H+ binding sites	1.8 M
$K_H^{B_H}$	H+ binding constant for the H+ binding sites	10−7.5 M

^aAll other model parameters were not changed from their original published values.