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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Oral Oncol. 2013 Jan 26;49(5):381–386. doi: 10.1016/j.oraloncology.2012.12.014

Table 1.

Origin of the fibroblasts used in studies reviewed in this article

Secreted Factor Source of fibroblasts Reference
Gene expression study Patient derived oral SCC [5]
BDNF Cancer-free human oral fibroblasts activated by exposure to oral SCC [7]
HGF Cancer-free human oral fibroblasts activated by exposure to oral SCC [9]
CCL7 Patient derived oral SCC [10]
PGE2 Cancer-free human dermal fibroblasts activated by exposure to pharyngeal or tongue SCC [11]
IL-1β Cancer-free human oral fibroblasts activated by exposure to oral SCC [12]
KGF Patient derived oral SCC [13]
Activin A Patient derived lingual SCC [14]
TGFβ Cancer-free human oral fibroblasts activated by exposure to oral SCC [21]
TGFβ Patient derived HNSCCs, various locations [22]
BMP4 Patient derived lingual, tonsilar and laryngeal SCC [24]
HGF Patient-derived lingual, tonsillar and laryngeal SCC [25]
MMPs Patient derived lingual and pharyngeal SCC [26]
MMPs Cancer-free human oral fibroblasts activated by exposure to oral SCC [27]
MMPs Patient derived oral and pharyngeal SCC [28]
MMPs Human gingival fibroblast from cancer free subjects [29]