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. Author manuscript; available in PMC: 2013 Apr 3.
Published in final edited form as: Cell Rep. 2013 Mar 14;3(3):831–843. doi: 10.1016/j.celrep.2013.02.009

Figure 4.

Figure 4

Development of hepatic steatosis by HFD is accelerated in S193D mice. A. A typical picture of H&E (left) and Oil Red O (right) staining of WT and S193D livers under HFD conditions. Upper image shows staining of the livers under normal diet (N diet). Scale bar: 40 μm. B and C. Amounts of TGs in serum and in livers of WT and S193D mice at different time points of HFD. Data from three animals of each genotype are presented as bar graphs. D. Amounts of DGAT1 and DGAT2 in livers after HFD. Western blotting was performed with protein extracts isolated at 3 and 12 weeks after initiation of HFD. Bar graphs show ratios of DGAT1 and DGAT2 to β-actin. E. Examination of DGAT2 expression in livers of WT and S193D mice by immunostaining. Bar graphs show the number of DGAT2-positive hepatocytes in livers of WT and S193D mice. Scale bar: 10 μm.