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. 2012 Dec 21;6(1):54–62. doi: 10.1007/s12254-012-0061-9

Table 5.

Treatment results according to presented features in all children treated in AML-BFM 2004 Interim study

Factors No. of total patients Overall survival ± SE (%) Event-free survival ± SE (%) No. of patients with achieved CR (%) Relapse-free survival ± SE (%)
5 year p-value 5 year p-value 5 year p-value
Gender
Male 130 63.9 ± 4.5 0.59 54.6 ± 4.6 0.24 119 62.5 ± 4.8 0.51
Female 107 62.1 ± 4.9 48.5 ± 5.1 88 65.3 ± 5.8
Age at diagnosis (year)
< 2 40 57.4 ± 7.8 0.47 45.7 ± 8.2 0.46 36 58.2 ± 9.2 0.36
2–10 62 68.5 ± 6.2 50.4 ± 6.6 53 63.7 ± 7.1
> 10 135 62.5 ± 4.5 54.3 ± 4.6 118 65.3 ± 4.9
WBC ´ 109
< 20 121 68.6 ± 4.5 0.31 62.3 ± 4.6 0.026 110 75.9 ± 4.6 0.003
20–100 75 56.8 ± 6.1 40.8 ± 6.2 63 50.2 ± 7.0
> 100 41 58.4 ± 8.0 40.9 ± 8.1 34 50.6 ± 9.4
FAB type
M0 21 66.9 ± 11.4 0.07 63.5 ± 11.3 0.16 18 67.9 ± 12.1 0.09
M1 32 63.3 ± 9.6 55.4 ± 9.5 28 65.2 ± 10.2
M2 66 68.7 ± 6.1 52.2 ± 6.3 62 61.3 ± 6.7
M3 20 74.6 ± 9.8 64.0 ± 12.9 16 82.9 ± 11.3
M4 48 66.2 ± 6.9 52.6 ± 7.4 43 65.6 ± 7.8
M5 36 43.9 ± 8.7 31.3 ± 8.4 29 42.9 ± 10.6
M6 + M7 14 53.8 ± 13.8 53.8 ± 13.8 11 88.9 ± 10.4

The values in italics denotes close statistical significance