Table 2.
Univariate ANCOVA Examining the Effects of Sex, Race, and Pubertal Status on Parameters of Lipolysis Estimated From the IM-FSIGT (n = 35 Boys and 77 Girls)a
| Variable entered | Insulin-Suppressed Lipolysis Rate (l2) |
Maximum Lipolysis Rate (l0 + l2) |
[Insulin] for 50% Suppression of Lipolysis (ED50) |
Fatty Acid Clearance Rate Constant (cf) |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| β | SE | P | β | SE | P | β | SE | P | β | SE | P | |
| Model with FM | ||||||||||||
| Sex | 1.32 | 1.79 | .46 | 1.30 | 1.80 | .47 | 1.12 | 2.77 | .68 | 0.02 | 0.01 | .02 |
| Race | −1.06 | 1.47 | .47 | −1.10 | 1.48 | .46 | 0.89 | 2.27 | .69 | −0.40c | 0.70c | .57 |
| Pubertal status | 4.82 | 2.04 | .02 | 4.72 | 2.04 | .02 | 2.23 | 3.14 | .48 | −0.01 | 0.01 | .41 |
| Height | 0.07 | 0.09 | .44 | 0.07 | 0.09 | .43 | 0.18 | 0.14 | .20 | 0.02c | 0.04c | .64 |
| Age | −1.51 | 0.56 | .01 | −1.51 | 0.56 | .01 | −1.00 | 0.86 | .25 | −0.22c | 0.27c | .43 |
| FM | 0.10 | 0.08 | .24 | 0.09 | 0.08 | .26 | 0.21 | 0.13 | .10 | −0.08c | 0.04c | .04 |
| P value for model with FM | .03 | .03 | .35 | .03 | ||||||||
| Model with LBM | ||||||||||||
| Sex | 1.52 | 1.99 | .44 | 1.46 | 2.00 | .47 | 0.02 | 0.04 | .54 | 0.40c | 0.88c | .65 |
| Race | −1.15 | 1.57 | .46 | −1.16 | 1.57 | .46 | 0.01 | 0.03 | .72 | 0.63c | 0.70c | .36 |
| Pubertal status | 4.74 | 2.11 | .03 | 4.67 | 2.12 | .03 | 0.02 | 0.04 | .63 | 0.31c | 0.93c | .74 |
| Height | 0.64 | 0.11 | .57 | 0.07 | 0.11 | .55 | 0.14c | 0.21c | .50 | 6.01d | 4.92d | .00 |
| Age | −1.55 | 0.58 | .01 | −1.54 | 0.58 | .01 | −0.02 | 0.01 | .13 | 4.88d | 0.25c | .85 |
| % FM | 0.20 | 0.19 | .30 | 0.20 | 0.19 | .31 | 0.48c | 0.36c | .13 | 0.14c | 8.47d | .47 |
| LBM | 0.10 | 0.11 | .39 | 0.09 | 0.11 | .44 | 0.33c | 0.21c | .12 | −0.24c | 5.02d | .00 |
| P value for model with LBM | .04 | .05 | .29 | .00 | ||||||||
| Model with REE | ||||||||||||
| Sex | 3.72 | 1.88 | .05 | 3.71 | 1.89 | .05 | 0.68 | 0.03 | .05 | 0.02 | 0.01 | .09 |
| Race | −1.12 | 1.46 | .44 | −1.16 | 1.46 | .43 | 0.02 | 0.03 | .38 | −0.48c | 0.01 | .51 |
| Pubertal status | 4.54 | 1.97 | .02 | 4.43 | 1.98 | .03 | 0.01 | 0.04 | .73 | −0.55c | 0.01 | .58 |
| Height | 0.04 | 0.09 | .66 | 0.04 | 0.09 | .65 | 0.10c | 0.17c | .56 | 3.59d | 4.65d | .44 |
| Age | −1.12 | 0.55 | .05 | −1.11 | 0.55 | .05 | −0.56 | 0.01 | .58 | −0.38c | 0.27c | .17 |
| FM | −0.04 | 0.09 | .64 | −0.05 | 0.09 | .61 | −8.16d | 0.17c | .64 | −2.65d | 4.70d | .57 |
| REE | 0.01 | 0.30c | .01 | 0.01 | 0.30c | .00 | 2.34d | 0.65d | .00 | −0.28d | 0.17d | .11 |
| P value for model with REE | .00 | .00 | .02 | .02 | ||||||||
| Model with FM and VAT | ||||||||||||
| Sex | 1.77 | 1.81 | .33 | 1.79 | 1.81 | .32 | 1.54 | 2.81 | .58 | 0.02 | 0.01 | .04 |
| Race | −0.26 | 1.55 | .86 | −0.23 | 1.55 | .88 | 1.58 | 2.40 | .51 | −0.01 | 0.01 | .21 |
| Pubertal status | 5.74 | 2.11 | .01 | 5.72 | 2.11 | .01 | 3.08 | 3.29 | .35 | −0.01 | 0.01 | .16 |
| Height | 0.10 | 0.09 | .30 | 0.10 | 0.09 | .29 | 0.20 | 0.14 | .16 | 0.45d | 4.40d | .92 |
| Age | −1.58 | 0.56 | .01 | −1.58 | 0.56 | .00 | −1.06 | 0.86 | .22 | −0.17c | 0.26c | .53 |
| FM | 0.03 | 0.09 | .76 | 0.02 | 0.09 | .85 | 0.15 | 0.14 | .30 | −3.52c | 4.38d | .42 |
| VATb | 6.07 | 3.92 | .12 | 6.64 | 3.93 | .09 | 5.37 | 6.10 | .38 | −0.04 | 0.02 | .04 |
| P value for model with VAT | .02 | .02 | .38 | .01 | ||||||||
Abbreviations: β, parameter estimate; FFM, fat-free mass.
Positive β indicates higher for girls and higher for NHW; bold text indicates significant effects (P < .05). For ANCOVA, pubertal status was divided into early (Tanner 1–3 breast development for girls; testis volume <12 mL for boys) and late (Tanner 4–5 breast development for girls; testis volume ≥12 mL for boys) groups.
For ANCOVA, VAT was log transformed to meet the homogeneity of variance assumption.
× 10−2.
× 10−4.