Table 3.
Liver injury characteristics stratified by preoperative therapy n (%)
| Regimen |
Liver toxicity (n = 51) |
Steatosis > 30% (n = 16) |
Sinusoidal dilation (n =31) |
Steatohepatitis (n = 20) |
||||||||
| Yes | No | 1P value | Yes | No | 1P value | Yes | No | 1P value | Yes | No | 1P value | |
| No CTx | 19 (35.8) | 34 (64.2) | 5 (9.4) | 48 (90.6) | 11 (20.8) | 42 (79.2) | 6 (11.3) | 47 (88.7) | ||||
| Oxaliplatin | 19 (57.6) | 14 (42.4) | 0.04 | 5 (15.2) | 28 (84.8) | NS | 14 (42.4) | 19 (57.6) | 0.03 | 7 (21.2) | 26 (78.8) | NS |
| Irinotecan | 5 (55.6) | 4 (44.4) | NS | 2 (22.2) | 7 (77.8) | NS | 1 (11.1) | 8 (88.9) | NS | 3 (33.3) | 6 (66.7) | 0.08 |
| HAI | 8 (72.7) | 3 (27.3) | 0.02 | 4 (36.4) | 7 (63.6) | 0.02 | 5 (45.5) | 6 (54.5) | 0.08 | 4 (36.4) | 7 (63.6) | 0.03 |
1Presence of liver injury characteristic; each chemotherapy group vs no chemotherapy. CTx: Chemotherapy; NS: Not significant; HAI: Hepatic artery infusion.