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. Author manuscript; available in PMC: 2013 Apr 3.
Published in final edited form as: Cell Cycle. 2010 Oct 9;9(19):4005–4012. doi: 10.4161/cc.9.19.13299

Figure 1.

Figure 1

Depletion of L37 stabilizes and induces p53. (A) U2OS and Saos2 cells were transfected with the indicated siRNAs, and the levels of the indicated proteins were determined 72 h later by immunoblotting. (B) percentage of S-phase cells in control (non-targeting) and L37 siRNA treated cells. Data were obtained 48 h after siRNA treatment. Data are shown as means ± SD of four independent experiments. ***Student’s t-test, p < 0.001. (C) U2OS cells were transfected with control (non-targeting) or L37 siRNAs and, 48 h later, cells were treated with cycloheximide (CHX) for the indicated periods of time. the indicated proteins were detected by immunoblotting.