Figure 1.

Schematic summary of the experimental designs for the OR task and SR task. On day 1 in both tasks, animals were given either test-pulse stimulation or HFS in the absence of any objects in the recording chamber to obtain the synaptic transmission profile of electrically induced plasticity without the tasks. After day 1, the tasks were presented simultaneously with test-pulse stimulation or HFS. In the OR task, the mice were exposed to 2 novel objects on day 2 (training phase) and to 1 familiar and 1 novel object on day 3 (test phase) at the same locations in the chamber to test for OR. Mice in the spatial object recognition (SR) task were exposed to 2 novel objects on day 2 (novelty exploration), then reexposed to the same objects at the same positions on day 3 (reexposure), and on day 4 (novel configuration), the same objects were repositioned to the other half of the contextually polarized chamber to test for SR of the objects. The tasks after day 1 were given simultaneously together with either test-pulse stimulation or HFS. The labels above the chambers indicate the different phases of the OR and SR tasks. Gray arrows represent the delay period between the individual phases of the tasks.