Table 4. Factors associated with radiation therapy (RT) response.
| Variables | No of patients | No of (+) response (%) | p-value |
| Sex | |||
| Male | 41 | 25 (61.0) | 1.000 |
| Female | 6 | 4 (66.7) | |
| ECOG performance | |||
| 0–1 | 41 | 26 (63.4) | 0.662 |
| ≥2 | 6 | 3 (50.0) | |
| Child–Pugh class | |||
| A | 39 | 25 (64.1) | 0.692 |
| B–C | 8 | 4 (50.0) | |
| AST | |||
| ≤80 | 37 | 27 (73.0) | 0.004 |
| >80 | 10 | 2 (20.0) | |
| ALT | |||
| ≤80 | 35 | 23 (65.7) | 0.493 |
| >80 | 12 | 6 (50.0) | |
| ALP | |||
| ≤150 | 37 | 23 (62.2) | 1.000 |
| >150 | 10 | 6 (60.0) | |
| RT dose (BED, α/β=10) | |||
| ≥55 Gy | 21 | 15 (71.4) | 0.245 |
| <55 Gy | 26 | 14 (53.8) | |
| Pre-treatment AFP | |||
| ≥400 | 35 | 23 (65.7) | 0.493 |
| <400 | 13 | 6 (50.0) | |
| Tumour size | |||
| <10 cm | 35 | 24 (68.6) | 0.095 |
| ≥10 cm | 12 | 5 (41.7) | |
| Number of tumours | |||
| Solitary | 23 | 16 (69.6) | 0.371 |
| Multiple | 24 | 13 (54.2) | |
| Ascites | |||
| Positive | 7 | 2 (28.6) | 0.089 |
| Negative | 40 | 27 (67.5) | |
| Pulmonary disease | |||
| Positive | 3 | 0 (0.0) | 0.050 |
| Negative | 44 | 29 (65.9) | |
| Ascites or pulmonary disease | |||
| Positive | 9 | 2 (22.2) | 0.018 |
| Negative | 38 | 27 (71.1) | |
| AFP decrement after RT | |||
| Positive | 26 | 20 (76.9) | 0.033 |
| Negative | 21 | 9 (42.9) | |
| CT/MRI fusion mismatch | |||
| Positive | 24 | 11 (45.8) | 0.036 |
| Negative | 23 | 18 (78.3) | |
AFP, alpha-fetoprotein; ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspate aminotransferase; BED, biologically effective dose; ECOG, Eastern Cooperative Oncology Group; LN, lymph node.