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. 2013 Jan;86(1021):20120302. doi: 10.1259/bjr.20120302

Table 5. Enhancement ratiosa owing to combination with a 10B-carrier.

10B-carrier Total cell population Quiescent cells
Surviving fraction=0.08
  BPA 1.95 (1.75–2.15)b
  BSH 1.3 (1.2–1.4)
Net micronucleus frequency=0.2
  BPA 2.0 (1.8–2.2) 1.7 (1.6–1.8)
  BSH 1.3 (1.2–1.4) 1.8 (1.65–1.95)
Net apoptosis frequency=0.06
 In whole cell fraction
  BPA 1.5 (1.4–1.6) 1.25 (1.15–1.35)
  BSH 1.4 (1.3–1.5) 1.35 (1.2–1.5)
 In pimonidazole-unlabelled cell fraction
  BPA 1.65 (1.5–1.8) 1.65 (1.5–1.8)
  BSH 1.5 (1.4–1.6) 1.7 (1.6–1.8)

BPA, boronophenylalanine-10B; BSH, sodium mercaptoundecahydrododecaborate-10B.

aThe ratio of the dose of radiation necessary to obtain each end point without a 10B-carrier to that needed to obtain each end point with a 10B-carrier.

bValues in parentheses are 95% confidence limits, determined using standard errors. When the ranges of 95% confidence limits showed no overlap between two values, the difference between the two values were significant (p<0.05) based on a χ2 test.