Table 2. Verified or predicted probable targets of the studied miRNAs that might be involved in the pathogenesis of HCV infection.
miRNA | Predicted target genes | KEGG pathway classification | Validated target genes | KEGG pathway classification |
---|---|---|---|---|
miR-320c | ATM ICAM1 ESR1 NR3C1 | NF-kappa B signaling pathway | ADAMTS5 | Regulator of cell invasion |
GHR INSR ITGB3 | PI3K-Akt signaling pathway | |||
CACNA1A | MAPK signaling pathway | |||
miR-483-5p | MAPK3 | MAPK3 | Giloma cell proliferation | |
SRF | MAPK signaling pathway Viral carcinogenesis |