Figure 3. A network of genes is required to obtain the pica phenotype of Q₅₆-YFP.

The genes uncovered in the genome-wide screen are depicted as squares. The size of each square corresponds to the quality of the hit in respect to the pQ56 system. Square colour represents group association (green: Group I, orange: Group II, blue: Group III). Known interactions of the genes are represented by edges. The width of the edges correlates to the confidence level, the colour reflects the type of evidence (purple: physical interaction, blue: text mining, grey: other method). The genes were clustered according to their annotated biological process contribution (Supplementary Table S3 for further details).