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. 2013 Mar 12;4:1571. doi: 10.1038/ncomms2575

Table 1. Survivor colonies and growth on GdnHCl abolish the effect of polyQ proteins on septins.

Morphology pQ0 normal colonies (% of cells) pQ56 normal colonies (% of cells) pQ56 large colony 1 (% of cells) pQ56 large colony 2 (% of cells) pQ56 large colony 3 (% of cells) pQ56 GdnHCl-treated colonies (% of cells)
No structure 22 17 20 25 24 45
Single ring 66 36 68 68 62 43
Granular 7 12 8 1 5 7
Single focus 4 12 3 4 7 4
≥2 Foci 1 23 1 2 2 1

The table summarizes the data (% of cells in each category) visualized in Fig. 5c and additional readouts for three weakly fluorescent survivor colonies, as well as GdnHCl-treated cells. The data indicate that pica escape and GdnHCl therapy equally abolish the pica phenotype also on a molecular level.