Table 2. Fitted parameters for the two final placental malaria models.
Parameter | Description (units) | Posterior median (95% credible interval) | |
---|---|---|---|
|
|
Infection-specific |
Infected-pregnancy-specific |
EIR in Ifakara Town | Mean number of infectious bites on adults per-person year | 324.7 (257.5, 410.0) | 296.4 (230.3, 370.1) |
EIR in Kilifi District | Mean number of infectious bites on adults per-person year | 11.9 (8.9, 15.6) | 11.8 (8.9, 15.6) |
1/τΑ | Mean duration of acute infection (days) | 53.7 (41.2, 65.2) | 50.6 (38.7, 63.9) |
1/τc | Mean duration of chronic infection (days) | 94.2 (73.5, 118.1) | 103.0 (81.9, 127.7) |
τP | Rate of progression through past stage placental infection (1 per day) | 0.0002 (0.0001, 0.0012) | 0.0002 (0.0001, 0.0012) |
v | Power parameter of infection-blocking immunity | 1.01 (0.51, 2.36) | 1.03 (0.47, 2.62) |
ξ | Offset power of infection-blocking immunity | 14.5. (8.3, 37.4) | 9.93 (5.22, 31.46) |
ψc | Power parameter of faster clearance of chronic infection | 2.23 (0.59, 9.68) | 1.72 (0.42, 7.72) |
πc | Offset power of faster clearance of chronic infection | 1.16 (0.31, 1.98) | 0.65 (0.05, 1.04) |
ρ | Proportion of infections leaving behind substantial pigment | 0.53 (0.20, 0.78) | 0.42 (0.11, 0.74) |