Table 1.
Gene ontology for clusters from unsupervised clustering
| Annotation | Bayes factor |
|---|---|
| Cluster A | |
|
| |
| GO:0009607 [4]: response to biotic stimulus | 46.51 |
| GO:0006955 [4]: immune response | 41.26 |
| GO:0006952 [5]: defense response | 40.17 |
| GO:0006950 [4]: response to stress | 30.89 |
| GO:0043207 [5]: response to external biotic stimulus | 30.78 |
| GO:0050776 [5]: regulation of immune response | 29.23 |
| GO:0009613 [5]: response to pest, pathogen or parasite | 28.57 |
| GO:0006954 [5]: inflammatory response | 28.11 |
| GO:0051246 [5]: regulation of protein metabolism | 26.57 |
|
| |
| Cluster B | |
|
| |
| GO:0007166 [5]: cell surface receptor linked signal transduction | 10.18 |
| GO:0050875 [3]: cellular physiological process | 9.89 |
| GO:0007186 [6]: G-protein coupled receptor protein signaling pathway | 9.88 |
| GO:0006810 [4]: transport | 7.07 |
| GO:0051234 [4]: establishment of localization | 7.04 |
| GO:0051179 [3]: localization | 6.83 |
| GO:0009581 [5]: detection of external stimulus | 6.74 |
| GO:0007600 [5]: sensory perception | 6.64 |
| GO:0050877 [4]: neurophysiological process | 6.06 |
| GO:0050896 [3]: response to stimulus | 5.78 |
|
| |
| Cluster C | |
|
| |
| GO:0000279 [6]: M phase | 14.29 |
| GO:0007049 [5]: cell cycle | 11.92 |
| GO:0000280 [7]: nuclear division | 11.34 |
| GO:0007067 [8]: mitosis | 9.91 |
| GO:0000087 [7]: M phase of mitotic cell cycle | 9.86 |
| GO:0030261 [7]: chromosome condensation | 9.85 |
| GO:0008283 [4]: cell proliferation | 9.38 |
| GO:0000278 [6]: mitotic cell cycle | 7.9 |
| GO:0000088 [9]: mitotic prophase | 5.48 |
| GO:0007076 [8]: mitotic chromosome condensation | 5.48 |
|
| |
| Cluster D | |
|
| |
| GO:0007155 [4]: cell adhesion | 13.98 |
| GO:0007600 [5]: sensory perception | 13.97 |
| GO:0007275 [2]: development | 13.64 |
| GO:0042330 [5]: taxis | 12.21 |
| GO:0006935 [6]: chemotaxis | 12.21 |
| GO:0009581 [5]: detection of external stimulus | 11.96 |
| GO:0006954 [5]: inflammatory response | 10.1 |
| GO:0009653 [3]: morphogenesis | 8.89 |
| GO:0009887 [4]: organogenesis | 7.86 |
| GO:0048513 [3]: organ development | 7.72 |
Individual genes from each of the four clusters identified by unsupervised clustering (Fig. 2A) were used to search in gene ontology resources to identify major classes of genes. GATHER was used to define the ontology of each cluster using the Bayes factor as a measure of significance.