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Representative Micro-CT images of trabecular bone microarchitecture in the distal femurs. (a) SHAM group, (b) OVX group, (c) E2 group, (d) ECH-L group, (e) ECH-M group, and (f) ECH-H group. The OVX rats presented notable reduction in the trabecular number, trabecular area compared with the SHAM rats. ECH and E2 partially prevented OVX-induced trabecular bone loss and significantly improved trabecular bone mass and microarchitecture.
